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CAV-1 reduction induces Janus kinase (JAK)/STAT pathway activation in psoriatic inflammation, leading to further keratinocyte proliferation and cytokine/chemokine production

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However, these treatments primarily address symptoms and lymphatic complications rather than the underlying adipose tissue abnormality

Antidepressant-like effects of agomelatine, melatonin and the NK1 receptor antagonist GR205171 in impulsive-related behaviour in rats