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Regular exercise, quality sleep and effective stress management help reduce oxidative stress and support natural antioxidant production
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Vit E phenolic hydroxyl groups interrupt lipid peroxidation chains, increasing GPx/SOD [548] and blocking TGF-1- Phosphorylated extracellular signal-regulated kinase(pERK), phosphorylated extracellular signal-regulated kinase (pSmad2), and phosphorylated c-Jun N-terminal kinase (pJNK) fibrosis signaling [549], while increasing Roseburia abundance [550]
It is the same mechanism that makes pyridoxine effective for pregnancy nausea, chemotherapy-induced nausea, and motion sickness