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Wang D, et al

B12 supplements are often used to treat or prevent deficiency, which can lead to symptoms such as fatigue, weakness, constipation, loss of appetite, and megaloblastic anemia

Odds of new-onset symptoms are significantly lower with GLP-1-RA treatment at 6 months for headache (OR 0.660), visual deficits (OR 0.423), cognitive deficits (OR 0.368), and acetazolamide use (OR 0.295)

Pickart, L., Vasquez-Soltero, J., & Margolina, A

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Dipeptidyl peptidase-4 (DPP-4), a plasma enzyme, rapidly metabolizes GLP-1 and GIP, rendering them inactive