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Attacks often begin in the early morning and reach a peak within 6 to 24 hours

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Defer use of NASCOBAL in patients with nasal congestion, allergic rhinitis, or upper respiratory infections until after symptoms have subsided

Although children have a higher percentage of detectable antibodies from natural infection than adults, natural immunity on a population level is insufficient in protecting kids, the ACIP said, as natural immunity protection is random and there is no way to protect who will get strong protection and who will get no protection from it