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As a footnote, the study was sponsored by Novo Nordisk

However, only a few preclinical studies have been carried out on the usefulness of SS-31 in the treatment of renal diseases, and only a single model has been used

The review would benefit from a bit more text on how this notion impacts the balance between desired therapeutic effects, "diluted" effects from dimer-mediated versus non-dimer effects, and undesired off-target effects (which are discussed some in terms of receptor specificity, but not in terms of anatomy, where the same dimer may have different effects in different brain regions). Response: We have added a new section title General treatment approaches before the concluding remarks

Muscle-focused treatments like BodyTone can address mild skin laxity and sagging by strengthening the muscle underneath

Without sufficient L-carnitine, this energy production pipeline grinds to a halt, leaving cells starved for power and highly vulnerable to metabolic stress and premature cell death

10.3389/fonc.2023.1181176