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Upon recognition of MSU crystals, the NLRP3 inflammasome is activated, leading to the cleavage of pro-inflammatory cytokines, specifically interleukin-1 (IL-1) and interleukin-18 (IL-18)

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Like nausea, diarrhea may improve over time with continued use of the medication

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Quick Answer: GLP-1s and Heart Health GLP-1 medications may support heart health indirectly by helping appropriate patients lose excess weight, improve blood sugar control, reduce visceral fat, and improve cardiometabolic markers such as blood pressure, triglycerides, waist circumference, and inflammation