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For example, amphotericin B, an antifungal with high toxicity and low solubility, was included in cyclodextrins in order to improve solubility and reduce adverse effects [39]

Source: NEJM 2023 Safety profile: The most common adverse events were gastrointestinal (nausea 58%, diarrhea 39%, vomiting 32% in the 12 mg group)

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