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The peptide enhances neutrophil chemotaxis while simultaneously promoting their apoptosis and clearance by macrophages, preventing the chronic inflammation that impairs healing

Nonetheless, under certain conditions, conformational epitopes may remain intact despite processing and digestion [115, 116]

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Preclinical evidence supports BPC-157s ability to: Heal gastric and intestinal ulcers Restore tight junction integrity in leaky gut models Protect against NSAID- and alcohol-induced GI damage Modulate inflammatory responses in colitis and Crohns Support microvascular circulation and enteric nerve health Across nearly all models of gastrointestinal injury, BPC-157 promoted effective healing without toxicity, making it one of the most promising peptides for gut repair. Sikiric, P

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