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Peroxisome proliferator-activated receptor gamma (PPAR), the target of miR-27b, is essential for the maturation of pig oocytes, whereas miR-202 is gonad-specific and may help avoid premature ovarian failure (POF) (Song et al., 2016)

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Endothelial-derived impaired PDGFR signaling results in microvascular reductions, decreased CBF, and accumulation of neurotoxic molecules from the blood, contributing to secondary neurodegeneration [45, 74]

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