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[7] The concentration of glutathione in the cytoplasm is significantly higher (ranging from 0.5-10 mM) compared to extracellular fluids (2-20 M), reaching levels up to 1000 times greater

Macrophage Nrf2 activates genes encoding CD36, heme oxygenase-1 and other stress proteins in response to oxLDLs and other byproducts of lipid peroxidation (240)

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173 The oxidative stress is regarded as one of the pathological mechanisms during initiation and progression of liver fibrosis/cirrhosis, alcoholic liver diseases, and non-alcoholic steatohepatitis

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