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Saudi J Gastroenterol

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People with a personal or family history of medullary thyroid cancer or multiple endocrine neoplasia syndrome type 2 (MEN2) may need to avoid GLP-1s due to a potential cancer risk seen in animal studies

Circulating plasma GLP-1 levels rise from approximately 510 pmol/L in the fasted state to 1550 pmol/L in the postprandial state, with peak levels depending on meal composition, caloric density, and rate of gastric emptying

[PubMed: 16529932] 187