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Moreover, PAP protected and reversed -cell necrosis and upregulated the mRNA expression of PI3K, GLUT4, and Akt in alloxan-induced diabetic mice ( Schisandra sphenanthera polysaccharides (SSPs) regulated hyperglycemia, improved the glucose tolerance, reduced FBG, and elevated the levels of FINS and the value of ISI in STZ induced rats

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These studies indicate that aspartate depletion might promote antitumor immunity and destabilize the tumor ECM

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Shiraishi Y, Fang P, Xu C, Song J, Krishnan S, Koay EJ, Mehran RJ, Hofstetter WL , Blum-Murphy M, Ajani JA, Komaki R, Minsky B, Mohan R, Hsu CC, Hobbs BP, Lin SH

Sept 14: After announcing Tuesday that its CRF1 antagonist, crinecerfont, met the primary efficacy endpoint in the Phase III CAHtalyst Adult Study for classic congenital adrenal hyperplasia, Neurocrine Biosciences reported good news on the neuro front