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They shed pounds with weight-loss jabs - but then came the loose skin Published After losing nearly six stone since December with the help of weight-loss injections, Emilly Murray has been left with an unwanted reminder of her former body - loose skin

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The antibody simtuzumab, targeting extracellular LOXL2, has undergone clinical trials in combination with gemcitabine for patients with metastatic pancreatic adenocarcinoma or with FOLFIRI (folinic acid, fluorouracil, and irinotecan) for patients with KRAS mutant colorectal cancer [102, 103]

For weight management, long-term adherence rates are the challenge