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These activated Smads form a complex with Smad4, which translocates to the nucleus and promotes the expression of pro-fibrotic genes [24], such as Type I Collagen alpha 1 (COL1A1) and Fibronectin and Connective Tissue Growth Factor (CTGF)

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Patients who receive consistent clinical oversight achieve better outcomes and stay on therapy longer

Des recherches supplmentaires sont ncessaires pour pouvoir faire des dclarations sur les effets long terme sur les personnes en bonne sant qui ne souffrent pas de maladies ou de dysfonctionnements crbraux