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In addition to mimicking GLP-1, it also activates GIP, another hormone involved in appetite, food intake and blood sugar regulation

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If any symptom feels overwhelming or starts to interfere with your daily life, dont tough it outreach out to your healthcare provider

In rodent models, Sema has been shown to activate GLP-1 receptors in the hypothalamus, indirectly affecting TSH (thyroid-stimulating hormone) levels and downstream thyroid hormone regulation

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certain medications including corticosteroids, antipsychotics (such as olanzapine, quetiapine), and some antidepressants (particularly mirtazapine) can increase appetite and potentially diminish semaglutide's effects