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Exenatide extended-release carries a boxed warning for thyroid C-cell tumors and is contraindicated in patients with personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2

Glucagon-like peptide-1 receptor signaling selectively regulates murine lymphocyte proliferation and maintenance of peripheral regulatory T cells

Mild nausea may return for a few days after each increase

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Clinical trial data showed gallbladder issues in 1.4% of participants, and all cases involved people eating very low-fat diets