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Research has investigated whether NNMT inhibition affects adipocyte metabolism, energy expenditure, and body weight in experimental systems

Digestive issues on holiday I recall being on holiday in Miami and just feeling "off." Id lost my appetite and felt a bit nauseous

Higher NNMT levels have also been observed in patients with some forms of muscular dystrophy [12]

Human evidence is still building

For example, 10 mg per week becomes 5 mg on Monday and 5 mg on Thursday

Deficiency develops gradually, as the body stores approximately 2-5 mg of B12 in the liver, which can sustain normal function for several years even with inadequate intake or absorption