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It has known nothing but sickness and poor health for so long that it is filled only with dysfunction, stress, negativity, cynicism, toxicity, fear, paranoia, anxiety, sadness, and instinctual behaviours of survival

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Early CVOTs on GLP-1RAs, such as the LEADER, Harmony Outcomes, REWIND, and SUSTAIN-6 trials, focused on patients with T2DM and demonstrated the cardioprotective effects of these agents, including liraglutide, albiglutide, dulaglutide, and semaglutide.[811] The potential cardiovascular benefits of GLP-1RAs in patients without diabetes remain an active area of research