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10.1016/j.neubiorev.2010.07.001 15 FiandacaM

Calcium, diacylglycerol, cAMP and various phosphate derivatives of myoinositol (phosphatidylinositol and others) are essential secondary messengers involved in the regulation of intracellular signaling cascades, in response to the activation of the TSHR, and are necessary for the production H 2 O 2 and TG synthesis (56)

Indeed, GCG antagonists, developed as potential glucose-lowering therapies, were associated with an increase in hepatic steatosis [38], suggesting that GCG agonists may reduce hepatic steatosis [39]

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Vitamin B12 is tested as part of a broader micronutrient panel that includes folate, vitamin B6, vitamin D, vitamin A, thiamine (B1), vitamin E, zinc, selenium, iron studies, and red cell folate