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Patients with high-sensitivity variants benefit from slower titration or microdose strategies, which can significantly reduce bloating while maintaining weight loss results

Diabetes treatment

Until more specific research is conducted, caution is advised

239 Studies have demonstrated that GLP-1 mediates several beneficial extrapancreatic actions on both tissues which either express GLP-1R or do not, 11 and clinical trials have found that some GLP-1-mimetic-based therapies alleviate T2D-associated cardiovascular diseases

appropriate patient screening before initiating treatment reduces these risks

Chen LL, Jaimes N, Barker CA, Busam KJ, Marghoob AA