anal fissures glp 1 An fissure is also called fissure in ano, anorectal fissure, it is a laceration or tear (open sore) formed in the bottom section of the anal canal near the anus and Anal Fissures: Symptoms, Causes, Diagnosis,

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Usually, patients with OC exhibit non-specific symptoms such as abdominal distension, pain, appetite loss, or increased frequency of urination during early development