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GLP-1 therapies uniquely tackle both conditions, delivering the 20.2% weight loss observed with tirzepatide compared with 13.7% for semaglutide in pivotal trials

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Moreover, the JAK-STAT pathway was enriched in the KEGG pathway analysis (Figure 8D)

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observed that treatment with coenzyme Q10 (CoQ10) or lipoic acid upregulated ATP and SOD levels, while decreasing apolipoprotein E and A in AD models