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Thus, convincing experimental evidence obtained from invertebrates and nonhuman vertebrates taught us that down-regulated IIS is of critical importance for metabolic homeostasis, improved oxidative stress responses and longevity

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By integrating HTS, in vitro, and in vivo methodologies, we aimed to unravel the complex genetic and molecular underpinnings of hair and nail biology, potentially leading to innovative treatments for various conditions related to these integumentary structures