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Results vary, but clinical studies and real-world data show that many individuals lose 5% to 10% of their body weight by the 12-week markespecially if they reach at least the 1 mg or 1.7 mg dose by that point

However, some individuals report skin changes during treatment

Ida, S., Kaneko, R., Imataka, K., Okubo, K., Shirakura, Y., Azuma, K., Fujiwara, R., & Murata, K

Adequate hydration, constipation prevention, proper hygiene, and awareness of symptoms provide robust protection against UTIs during semaglutide treatment

Semaglutide acts solely as a GLP-1 receptor agonist

Storage conditions directly affect potency, and degraded semaglutide can deliver less active compound per milligram than the label states