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Mitochondria-targeted inhibitors of the human SIRT3 lysine deacetylase

Ketamine action on astrocytes provides new insights into rapid antidepressant mechanisms

doi:10.2527/jas.2016-0478 Note: Originally published in April 2017, this article has been revised and updated for accuracy and thoroughness.

Never add any supplements to your plan until it has been assessed and approved by your medical doctor or a suitable qualified practitioner who is familiar with your health history

The expression of GST A3-3 in steroidogenic tissues suggests that the enzyme has evolved to support the activity of 3-hydroxysteroid dehydrogenase, which catalyzes the formation of 5-androsten-3,17-dione and 5-pregnen-3,20-dione that are substrates for the double-bond isomerization catalyzed by GST A3-3