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Clinical impression in descending order was pigmented macules (n = 15, 45%), melanosis (n = 4, 12%), nevus (n = 3, 9%), melanoma (n = 2, 6%), melanoacanthoma (n = 1, 3%), and racial pigmentation (n = 1, 3%)

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However, it also showed anti-inflammatory actions, such as inhibition of 5- and 15-lipoxygenases (LOX), NOS, and phagocyte-related ROS production (Section 11.2)

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Figure 2 shows the distribution of the years of publication of the 50 studies in this review