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Increase in the protein-bound form of glutathione in human blood after the oral administration of glutathione

Cellular Proliferation: Given IGF-1s role in promoting cellular proliferation and survival, long-term safety factors include possible effects on cell growth in many tissues

[14] [15] Patients with UC require careful monitoring of nutritional status, as chronic inflammation and diarrhea can lead to malabsorption, anemia, and weight loss

Concomitant medications may affect response

PMID: 7835211

This multi-system mechanism means dosing must be individualized based on renal function, cardiovascular history, diabetes status, and prior medication responses