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Metformin alleviates spinal cord injury by inhibiting nerve cell ferroptosis through upregulation of heme oxygenase-1 expression

Hopefully the dermatologist I see will have some familiarity or understanding of this

Interestingly, NK cells pretreated with REV exhibited increased GPX4 protein expression, increasing to the sensitivity of breast cancer cells to ferroptosis and thereby promoting the antitumor activity of NK cells (163)

[DOI] [PubMed] [Google Scholar] 42.Caldas E.D., Silva A.C.S

10.1074/jbc.M100754200

It exerts a protective effect by scavenging peroxynitrite and preventing the release of AIF and EndoG from mitochondria and subsequent nuclear DNA breakage ( Tannins is well-known for its anti-oxidative stress activity