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Overlapping conditions like Asthma-COPD Overlap Syndrome (ACOS) cannot be ignored because this is linked to higher BMI, poorer lung function, and a greater risk of frequent and severe acute exacerbations, as well as a higher number of exacerbations per year compared to patients with pure COPD

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This is the direct reason the two are best supplied as two separate 5mg vials rather than a single pre-blended one

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Protein synthesis: GH stimulates IGF-1 production in the liver and locally in muscle tissue