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Biochemistry 48, 1110811116

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9 Causes of Low Vitamin B12 Age Older adults are at a greater risk of a B12 deficiency due to poor absorption

In the liver, the 25-hydroxylase enzymes (CYP2R1 and CYP27A1) convert inactive cholecalciferol to 25(OH)VD 3 (calcidiol) by carbon 25 hydroxylation 14

These tumor cells can not consume isocitrate to produce -KG but convert -KG to 2-hydroxyglutaric acid (2-HG)

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