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Metabolic reprogramming further exacerbates immunosuppression, such as the conversion of extracellular ATP to adenosine mediated by the CD39/CD73 axis, which not only inhibits CTL function but also promotes T cell exhaustion by activating the adenosine A2A receptor (ADORA2A) (207)

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[DOI] [PubMed] [Google Scholar] 158.Alexopoulos P., Sorg C., Frschler A., Grimmer T., Skokou M., Wohlschlger A., Perneczky R., Zimmer C., Kurz A., Preibisch C

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