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Contraindicated in patients with a history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia Syndromes (MEN 2) Consult your healthcare provider if you have a history of pancreatitis, as the medication may increase risk Serious side effects may involve hypoglycemia, kidney issues, or allergic reactions 1,5 Not suitable for individuals with type 1 diabetes or diabetic ketoacidosis Medication interactions may occur with those on insulin, oral diabetes medications, oral contraceptives, and blood thinners

Summary: The correct dosage of B12 for healthy UK adults is 1.5 micrograms daily for maintenance, whilst treatment of deficiency requires substantially higher doses of 1,0002,000 g orally or 1 mg intramuscular injections

10.1056/nejm199004123221502 50 KawamuraE.EnomotoM.KotaniK.HagiharaA.FujiiH.KobayashiS.et al (2012)