asa guidelines glp-1 Perioperative anesthesia management of receptor agonists: a systematic review of potential risks | Perioperative Medicine 2025 ADS/ANZCA/GESA/NACOS clinical practice recommendations

Too low brain isnt getting enough stimulation fatigue persists Too high nervous system overstimulation eventual crash and exhaustion Signs your dose may be off: Feeling wired but exhausted Heavy brain or emotional numbness Needing caffeine to push through the day Fatigue doesnt always mean you need more sometimes it means you need less or different timing

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Although the pathogenesis of AA is understood to involve disruption of the hair follicle immune privilege (Mo et al