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IC 50 = 0.16 g/mL) decreased IgE production by IgE-producing myeloma cells U266 without causing cytotoxicity [120]

Age over 65 also increases vulnerability due to thinner intestinal tissue and reduced healing capacity

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Adjunct Cancer Therapy (Experimental) Some studies suggest that high-dose intravenous vitamin C may help reduce chemotherapy side effects and improve the quality of life in cancer patients

The receptor also shows notably high constitutive (ligand-independent) activity, a feature that distinguishes it from many other G-protein-coupled receptors and that shapes how agonists like MK-677 behave