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high-dose oral B12 can be effective for many causes of deficiency Sublingual (under the tongue) preparations : Though marketed as having better absorption, evidence does not show clear advantages over standard oral tablets Intramuscular injections : Prescribed for those with absorption problems or severe deficiency
What makes this mechanism notable is its specificity
PMID 37973897
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Although the connection between the two isnt yet fully understood, research suggests that low levels of B-12 may be linked to an increased risk of depression, and that maintaining adequate levels could support better treatment outcomes
PMID: 34377956
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