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Clinical trials demonstrate that patients experience comparable weight loss outcomes when using equivalent doses of semaglutide from either source

Start: Begin at 0.25 mg (gradual) or 0.6 mg (advanced) weekly to settle tolerability [1] [4]

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Looking for the next step in obesity pharmacotherapies, the concept of combining entero-pancreatic hormones for obesity treatment was supported by the marked WL, sustained weight maintenance, and metabolic benefits observed with BS, which increase multiple gut hormone levels [9,10,11,12,13,14]