glp 1 seizures GLP-1 drugs linked to reduced risk of epilepsy GLP-1 medication and seizure risk?

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10.1089/ars.2009.2899 50 YangW.YangG.JiaX.WuL.WangR

Peripheral artery disease (PAD) is a progressive condition characterized by abnormal narrowing and blocking of blood vessels, which is associated with an increased risk of myocardial infarction, stroke, and cardiovascular disease-related mortality

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Mechanistically, macrophage-specific inhibition of GLUL leads to accumulation of succinate and HIF-1 via glutamine-dependent -aminobutyric acid (GABA) shunting (thereby inhibiting vessel sprouting and metastasis) and via stimulation of T effector cells

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