Approximately 60% of Rett syndrome patients meet the criteria for ASD, characterized by repetitive hand movements, social withdrawal, and loss of language communication
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and seed funds from the NIH National Center for Advancing Translational Science Clinical and Translational Science Award (UL1TR001085), SPARK (a translational research programme at Stanford), Weston Havens Foundation, and the Stanford Child Health Research Institute Transdisciplinary Initiatives (TIP) grant
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A significant negative latitude-dependent relationship was detected for carriage of the T allele, with occurrence of the cSHMT-C1420T polymorphic allele decreasing with increase in latitude ( r 2 =0.73, p 3R frequency in reported African and Eurasia studies found a significant negative relationship between latitude and frequency of the 3R allele ( r 2 =0.12, p =0.039) (Fig
