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We explored what responsible-AI means in clinical contexts: from realistic threat models (with evidences) and jailbreak scenarios to aligning systems with general & clinical values alongside establishing practical guardrails through evaluation, red-teaming, documentation, and governance

IGF-1R Receptor Binding and Downstream Signalling Both IGF-1 and des-(1-3)IGF-1 bind only to the type 1 IGF receptor in L6 myoblasts, rat vascular smooth-muscle cells, and human lung fibroblasts, with binding potencies in the order des-(1-3)IGF-1 greater than IGF-1 a difference attributed to the lower affinity of des-(1-3)IGF-1 for the competing IGFBP rather than superior intrinsic receptor affinity

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DEXA scans are considered the gold standard