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But as degradation progresses, visible and functional signs emerge

Experiments on mouse chondrocytes also revealed the added role of liraglutide in reducing inflammation by decreasing mRNA expression of inducible nitric oxide synthase, matrix metallopeptidase 13, and ADAM metallopeptidase with thrombospondin type 1 motif 5, culminating in a reduction of IL-6, prostaglandin E2, and nitric oxide[13]

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2008;34:S65-72