when was semaglutide fda approved Approves for New Indication Involving Cardiovascular Disease Is Semaglutide GLP-1 Safe for

Black Box Warning GLP-1 receptor agonists, including semaglutide, carry a black box warning for the risk of thyroid C-cell tumors, based on findings in animal studies

Most are gut-related, like nausea, heartburn, and diarrhea or constipation

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However, our analysis revealed the opposite: patients with diabetes who were exposed to GLP-1 RAs had a substantially higher risk of being diagnosed with nAMD, with a shorter time to diagnosis, compared with propensity-matched patients who were unexposed. The researchers also revealed that this finding comes amid numerous reports in other literature of unexpected worsening of diabetic retinopathy following a rapid reduction in blood glucose levels

Different biology, different timeline, different metrics