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J Appl Biobehav Res

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This is why two people with the same testosterone level can have profoundly different libido experiences: one person's dopamine reward system responds to sexual stimuli with robust incentive salience and sustained motivational drive

A change in diabetes drug prescribing led to clinical trials of intranasal insulin administration, followed by insulin sensitizers, including metformin and peroxisome proliferator-activated receptor agonists, followed by incretin mimetics targeting primarily GLP-1R (GLP-1RAs) [106]

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however, it can occur anywhere in the peripheral nervous system [6, 8, 9]