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10.1097/MD.0000000000015180 88 SjominaO.PoakaI.SuhorukovaJ.VangravsR.ParutinsS.KnazeV.et al (2024)

(2017) observed that TMAO treatment promoted monocyte adhesion through upregulation of vascular cell adhesion molecule-1 (VCAM-1) but not the other adhesion molecules (i.e., intercellular adhesion molecule-1 (ICAM-1) and E-selectin) expression in human umbilical vein endothelial cells in vitro

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Storing the vial in its original box or in a dark part of the refrigerator provides an extra layer of protection

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Multiple experimental and clinical trials have preliminarily confirmed TCMs efficacy and safety