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Research indicates that individuals with BP-I remain symptomatic for nearly half of their illness course, with depressive symptoms being the most frequent and persistent, significantly outweighing manic/hypomanic and mixed episodes (Nierenberg et al., 2023)

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Endogenous importance does not validate every product Water, glucose and insulin are also endogenous or physiologically essential, but their medical effects depend on dose, route, formulation, diagnosis and product quality

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Conversely, KLOWs specificity is a limitation if the research goal is systemic rejuvenation

Folate is also involved in the production of healthy red blood cells.) that deliver oxygen and nutrients to your tissues, and in the conversion of the amino acid homocysteine into methionine