tirzepatide and blood pressure Will Lower Pressure? UK Clinical Evidence What is Tirzepatide? 👇 A

4 Discussion The main findings of the present studies are the following: (1) the pharmacokinetics of icodec are unchanged when combining icodec and semaglutide in IcoSema, (2) the total exposure of semaglutide in IcoSema is unchanged, but the maximum concentration is higher and earlier compared with semaglutide administration alone, (3) the change in semaglutide pharmacokinetics in IcoSema appears to be owing to competition for albumin binding locally at the injection site, where icodec outcompetes semaglutide and (4) the frequency of gastrointestinal related adverse events is higher for IcoSema versus icodec or semaglutide administration alone

The EMPA-REG OUTCOME trial showed that empagliflozin markedly reduced the risk of CV mortality compared to that observed with placebo [8]

We just don't know them yet What amazes me is that people are surprised by this

Biomark 3 , 4 (2014)

Systemic semaglutide provides a mild vasoprotective and antineuroinflammatory effect in a rat model of ocular hypertensive glaucoma

But do not ignore it either