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The residue was diluted with ethyl acetate (100 mL) and deionized water (200 mL)

Furthermore, a placebo-controlled randomized trial evaluated the efficacy of folinic acid (5 mg twice daily) for 12 weeks in 19 children aged 310 years (sex distribution not reported) with ASD diagnosed by ADOS, without genetic syndromes, major medical comorbidities, or treatments affecting folate metabolism

Adverse reactions reported following methylcobalamin administration include headache, infection, nausea/vomiting, paresthesias, and rhinitis

These are typically mild to moderate and tend to decrease as the body adjusts to the medication over the first several weeks of treatment

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