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Marshall B, Warren JR (1984) Unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration

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The CagriSema program is the closest large-scale proof of concept the field has

Moreover, the R17 Cagri- E14 Cagri ionic lock was present in the bypass conformation but absent in the CT-like conformation in both CagriBB-bound structures, consistent with a higher energy requirement to form the CT-like conformation (Supplementary Fig