Furthermore, comparing Prdx Km for H 2 O 2 with that of GPx and catalase exceeding even the millimolar range [180] suggests that the role of Prdx is rather as a sensor of H 2 O 2 [178] than oxidative stress condition reversal
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Almost 200 years later in 1885, Paul Ehrlich observed that the trypan blue dye, when given in the blood circulation in rats, stained only peripheral organs not the brain and spinal cord [1, 2]
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