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Ca 2+ acts as a key second messenger in regulating various physiological changes during capacitation, including hyperactivation of motility (Snchez-Crdenas et al., 2018), membrane fluidity alterations, and the activation of signaling cascades essential for the acrosome reaction (Buffone et al., 2014)

Anticancer Drugs 24(9):881888 Dorai T, Dorai B, Pinto JT, Grasso M, Cooper AJL (2020) High levels of glutaminase II pathway enzymes in normal and cancerous prostate suggest a role in glutamine addiction