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Supply and cost constraints have led some companies to formulate compounded semaglutides

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NAC reduces the size and activity of vWF helping prevent clots

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Medications such as semaglutide the active ingredient in Ozempic and Wegovy are designed to mimic this effect in a much stronger and more sustained way

in Spain, its current prevalence ranges between 2833%11,12 and it is a recognized as a cardiovascular risk factor and increases the mortality in this population.1315 Furthermore, in patients with DM2 and advanced CKD there are limitations in the prescription of certain antihyperglycemic drugs (e.g., metformin or sulfonylureas) and there is an increased risk of hypoglycemia with antihyperglycemic treatment,16 a complication that is associated with increased cardiovascular risk17 and hinders the achievement of glycemic control targets